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ATX motherboard with silver heatsinks and black PCB

ASUS

ASUS PRIME TRX40-PRO S AMD motherboard

SKU CH-CCKE-JJQM2

ATX board for third-generation AMD Ryzen Threadripper CPUs with eight DDR4 slots supporting up to 256GB, three PCIe 4.0 x16 slots, three M.2 sockets, eight SATA ports.

  • ProcessorAMD sTRX4
  • ChipsetAMD TRX40
  • Form factorATX
  • CPU socketsTRX4
  • Memory slot count8 × 288pin (DDR4)
  • Supported memoryDDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.
  • Supports 3rd Gen Ryzen Threadripper CPUs via sTRX4 socket
  • Eight DDR4 slots deliver up to 256 GB quad-channel memory
  • Three PCIe 4.0 x16 SafeSlots for multi-GPU or add-in cards
  • Three M.2 sockets plus eight SATA 6Gb/s ports for high-capacity storage
  • Intel I211AT LAN and Realtek ALC1220 8-channel audio for wired networking and sound

sTRX4 Threadripper Workstation Board

The ASUS PRIME TRX40-PRO S is an ATX motherboard built around the AMD TRX40 chipset for 3rd Gen Ryzen Threadripper processors. It targets professionals who need high core counts and large memory capacity in a standard form factor.

Eight DDR4 Slots Up to 256GB

Creators and engineers running memory-intensive workloads benefit from eight 288-pin slots supporting quad-channel DDR4 up to 4666 MHz O.C. and 256GB total. Builds requiring ECC UDIMM support are covered. Systems needing registered ECC or more than eight DIMMs should choose a WRX80 platform instead.

Three PCIe 4.0 x16 SafeSlots

The board provides three reinforced PCIe 4.0 x16 slots wired for x16/x16/x16 operation with recommended 3rd Gen Threadripper CPUs. This layout decides whether multi-GPU compute or multiple high-bandwidth add-in cards will fit without sharing bandwidth.

How it compares

Measured against everything we stock in Motherboards for AMD CPUs, at today’s prices. Recalculated every night.

Price $341.99
Pricier than about 59% of the 1,906 comparable items (median $224.49).

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Specifications

Product
Brand nameASUS
Product lineTRX40
Model namePRIME TRX40-PRO S
Processor
ProcessorAMD sTRX4
CPU socketsTRX4
ChipsetAMD TRX40
Memory
Memory slot count8 × 288pin (DDR4)
Supported memoryDDR4 4666(O.C.)/ 4600(O.C)/ 4400(O.C)/ 4333(O.C.)/ 4266(O.C.)/ 4133(O.C.)/ 3800(O.C.)/ 3733(O.C.)/ 3466(O.C.)/ 3400(O.C.)/ 3200/ 2933/ 2800/ 2666/ 2400/ 2133 MHz ECC and non-ECC, Un-buffered Memory
Max supported RAM256 GB
Memory channelsQuad Channel
Storage
SATA ports8 x SATA 6Gb/s
M.2 slots3rd Gen AMD Ryzen Threadripper Series Desktop processors: 2 x M.2 Socket 3, with M key, type 2242/2260/2280/22110 storage devices support (PCIe 4.0 x4 mode) AMD TRX40 chipset: 1 x M.2 Socket 3, with vertical M key, type 2242/2260/2280/22110 storage devices support (SATA & PCIe 4.0 x4 mode)
SATA and RAID support0/1/10
Audio & video
Audio chipRealtek ALC S1220 High Definition Audio CODEC featuring Crystal Sound 3
Sound channels8 Channels
Connectivity
Ethernet controllerIntel i211AT
Maximum network speed1 Gbit/s
Ports & slots
PCIe x4 slotsAMD TRX40 chipset: 1 x PCIe 4.0 (x4 mode)
Additional slots1 x M.2 Socket (Key E), supports type 2230 PCIe Wi-Fi/BT module* * The Wi-Fi/BT module is purchased separately
Onboard USB headers1 x USB 3.2 Gen 2 front panel Type-C connector 2 x USB 3.2 Gen 1 connectors support additional 4 USB ports (19-pin) 2 x USB 2.0 connectors support additional 4 USB ports
Power
Power connectors1 × 24-pin EATX Power connector(s) 2 × 8-pin ATX 12 V Power connector(s)
Size & build
Form factorATX
Width and length12.0 in × 9.6 in
Compatibility
Windows 11 supportSupported
More details
LightingRGB

Questions about this item

Will this board take my existing DDR4 ECC modules?

Yes, the eight 288-pin slots accept both ECC and non-ECC un-buffered DDR4 up to 256 GB total in quad-channel mode.

How many full-length graphics cards can run at x16 speed?

Three PCIe 4.0 x16 SafeSlots support x16/x16/x16 mode with a 3rd Gen Threadripper CPU; using the first and second or first and third slots is recommended for two cards.

What M.2 drives fit the three onboard slots?

Two CPU-linked slots take 2242, 2260, 2280 and 22110 M-key drives at PCIe 4.0 x4; the chipset slot is a vertical M-key 2280/22110 also at PCIe 4.0 x4.

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