HPE ML350 Gen10 4LFF rack server 2x Xeon Silver 4210 512GB DDR4 no drive

HPE ML350 Gen10 4LFF dual Xeon server

The HPE ML350 Gen10 4LFF is a rack-mounted server system built for businesses that need expandable compute and memory in a 4U form factor. It arrives with two Intel Xeon Silver 4210 processors running at 2.2GHz, each offering 10 cores and 13.75 MB cache. Installed memory totals 512GB of DDR4 ECC registered DIMMs, leaving headroom toward the 3TB maximum capacity. The chassis supports up to four 3.5-inch drive bays for SATA or SAS storage.

Verify rack space power and drive requirements

Confirm that your rack can accommodate a unit measuring 36 x 24 x 10 inches and weighing 40 units. The system includes two 500W Flex Slot power supplies, so ensure your PDU delivers compatible connections and sufficient capacity for the configured load. No drives are installed; you must supply 3.5-inch SATA or SAS drives that match the Smart Array P408 controller interface. Network connectivity uses an Intel I350/X540 card providing two 10GbE and two 1GbE ports, so plan cabling and switch ports accordingly.

Integrates with iLO management and flexible storage

Remote administration is handled through HPE iLO Advanced, allowing out-of-band monitoring and firmware updates without a local console. The P408 SAS controller manages RAID across the four drive bays, freeing the CPU for application workloads. Integrated graphics provide basic video output for initial setup, while the dual 10GbE ports reduce the need for additional network adapters. Rail kits are available separately to simplify rack installation.