HPE ProLiant ML350 Gen10 8SFF 2x Xeon Silver 4216 64GB DDR4 rack server

Dual Xeon 4216 rack server

The HPE ProLiant ML350 Gen10 arrives with two Xeon Silver 4216 processors running at 2.1GHz and 64GB of DDR4 ECC registered memory. The 8SFF chassis supports up to eight 2.5in SAS drives behind an HPE Smart Array P408 controller. Integrated iLO Advanced remote management and a quad-port Intel network card with two 10GbE and two 1GbE links complete the baseline configuration. Dual 500W Flex Slot power supplies provide redundancy from day one.

Scales from single-socket

Organisations running single-processor Gen9 towers or earlier ML350 models gain 16 additional cores and 22MB of extra cache per socket without changing rack footprint. The jump is worth it when virtualisation density, database threading or container counts exceed what a single Silver 4216 can sustain. Buyers who need more than 3TB of memory or more than two sockets should evaluate a different platform because this chassis maxes out at two processors and the stated memory ceiling.

Steady output under continuous multi-threaded load

Burn-in testing confirms both CPUs hold their 2.1GHz base frequency across all 16 cores per socket while the P408 controller drives sustained SAS throughput. The twin 500W supplies share load evenly, keeping thermal headroom inside the 36x24x10in enclosure. iLO Advanced telemetry streams real-time power and temperature data so operators can correlate workload spikes with hardware health before thresholds are breached.