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Black rectangular ATX motherboard with silver heatsinks and black PCB visible in top-down view

ASUS

ASUS ROG STRIX X299-E GAMING II Intel motherboard

SKU CH-ZE94-NC2BZ

LGA 2066 ATX board with Intel X299 chipset supports 256 GB DDR4 and multi-GPU PCIe 3.0 layouts

  • ProcessorIntel Socket 2066 Core X-Series Processor
  • ChipsetIntel X299
  • CPU socketLGA 2066
  • Supported memoryDDR4 4266 (overclocking)/4200 (overclocking)/4133 (overclock
  • Max supported RAM256 GB
  • PCI slots3 x PCIe 3.0 x16 (x16, x16/x16, x16/x16/x8) 3 x PCIe 3.0 x16
  • Supports up to 256GB DDR4 memory capacity
  • 120dB SNR stereo playback for high-fidelity audio
  • Dual Intel and Realtek 2.5G LAN controllers
  • Four USB 3.2 Gen 2 ports up to 10Gbps
  • Three PCIe 3.0 x16 slots for multi-GPU setups

ASUS ROG STRIX X299-E GAMING II Motherboard

This ATX board uses the Intel X299 chipset and an LGA 2066 socket for Core X-Series processors. It targets enthusiasts and workstation builders who need high core counts and large memory capacity. The board supports up to 256GB of DDR4 memory across eight slots. It is built for multi-GPU configurations and high-speed storage arrays.

Upgrade Path for X299 Platform Users

The board replaces an older X299 model when you need more robust power delivery or additional connectivity. The jump is worth it if your current board limits memory speed or lacks the 2.5G LAN controller. It also adds four USB 3.2 Gen 2 ports at 10Gbps for faster external drives. Builders moving to 9000-series CPUs will find native support here.

Build Integration and Expansion

The layout provides three PCIe 3.0 x16 slots that run at x16, x16/x16, or x16/x16/x8 depending on the CPU. Eight SATA III ports and two M.2 interfaces handle large storage pools. SupremeFX audio with 120dB SNR output and dual headphone amplifiers serves monitoring needs. Intel I219V and Realtek 8125 2.5G LAN handle wired networking.

How it compares

Measured against everything we stock in Motherboards for Intel CPUs, at today’s prices. Recalculated every night.

Price $203.99
Pricier than about 82% of the 2,965 comparable items (median $97.99).

New to this? Buying PC parts with Monero — what to check, what it costs to pay, and what is never asked for.

Specifications

Product
Brand nameASUS
Product lineASUS ROG STRIX X299-E GAMING II
Model nameASUS ROG STRIX X299-E GAMING II
Processor
ProcessorIntel Socket 2066 Core X-Series Processor
CPU socketLGA 2066
ChipsetIntel X299
Memory
Supported memoryDDR4 4266 (overclocking)/4200 (overclocking)/4133 (overclocking)/4000 (overclocking)/3866 (overclocking)/3733 (overclocking)/3600 (overclocking)/3466 (overclocking)/3400 (overclocking)/3333 (overclocking)/3300 (overclocking)/3200 (overclocking)/2800 (overclocking)/2666/2400/2133 MHz memory
Max supported RAM256 GB
Storage
SATA and RAID support2XM.2 interface, 8xSATA III interface
Connectivity
Ethernet controllerIntel I219 V
Realtek RTL8125-CG 2.5G LAN
Anti-surge LANGuard
ROG GameFirst Technology
Ports & slots
PCI slots3 x PCIe 3.0 x16 (x16, x16/x16, x16/x16/x8)
3 x PCIe 3.0 x16 ( x16, x16/x8, x16/x8/x4)
1 x PCIe 3.0 x1 *1
3 x PCIe 3.0 x16 (x16, x16/x16, x16/x16/x4)
(Intel Core i9 9000/7000 and i7 9000 X-Series CPU)
(Intel Core i7 7000 X-Series CPU)
48-Lane CPU-
44-Lane CPU-
28-Lane CPU-
Intel X299 Chipset
1 x PCIe 3.0 x4
Onboard USB headers4 x USB 3.2 Gen 2 (up to 10 Gbit/s) ports (4 on backplane, 3 x Type-A + 1 x Type-C)
6 x USB 3.2 Gen 1 (up to 5 Gbit/s) ports (2 in backplane, 4 in motherboard)
ASMedia USB 3.2 Gen 2 controller :
Intel X299 Chipset :
8 x USB 2.0 ports (4 in backplane, 4 in motherboard)
1 x USB 3.2 Gen 2 front panel connector

Questions about this item

What are the ATX dimensions of this board so I can confirm it fits my case?

The board measures 30.5 cm by 24.4 cm, matching the standard ATX form factor for compatible cases

Which CPU power connectors must be seated for the LGA 2066 socket, and what is the common oversight?

Connect both the 8-pin and 4-pin EPS plugs; the extra 4-pin is often missed but required for stable power delivery to Core X-Series processors

What replaceable component on the board maintains BIOS settings when the system is unplugged?

A removable metal battery holder is included; swap the cell when the clock drifts or BIOS defaults reappear after power loss

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